Publications – Park Research Lab

Park Research Group

Publications

[1] Visible Light-Driven, Iridium-Catalyzed Hydrogen Atom Transfer: Mechanistic Studies, Identification of Intermediates and Catalyst Improvements.

Park, Y.†; Tian, L.†; Kim, S.; Pabst, T. P.; Kim, J.; Scholes, G. D.; Chirik, P. J.

JACS Au 2022, 2, 407-418 (†Co-first authors).

[29] Iridium-Catalyzed Chemo-, Diastereo-, and Enantioselelctive Allyl-Allyl Coupling: Accessing All Four Stereoisomers of (E)-1-Boryl-Substituted 1,5-Dienes by Chirality Pairing.

Yongsuk Jung,^† Seok Yeol Yoo,^† Yonghoon Jin, Jaehyun You,^‡ Seungcheol Han, Jeongwoo Yu, Yoonsu Park,* Seung Hwan Cho*

Angew. Chem. Int. Ed. 2023, e202218794 (^†Co-first authors, ^‡Undergraduate).

Selected as a Hot Paper.

Postdoc Works

The Park Laboratory

Postdoc Works

[28] Pentamethylcyclopentadienyl Metalloradical Iron Complexes Containing Redox Noninnocent α-Diimine-type Ligands: Synthesis, Molecular and Electronic Structures.

Park, Y.; Zhong, H.; Pabst, T. P.; Kim, J.; Chirik, P. J.

Organometallics 2023, 42, 465-472.

[27] Ammonia synthesis by photocatalytic hydrogenation of a N₂-derived molybdenum nitride.

Kim, S.; Park, Y.; Kim, J.; Pabst, T. P.; Chirik, P. J.

Nature Synth. 2022, 1, 297-303.

[26] Visible Light-Driven, Iridium-Catalyzed Hydrogen Atom Transfer: Mechanistic Studies, Identification of Intermediates and Catalyst Improvements.

Park, Y.†; Tian, L.†; Kim, S.; Pabst, T. P.; Kim, J.; Scholes, G. D.; Chirik, P. J.

JACS Au 2022, 2, 407-418 (†Co-first authors).

[25] Visible Light Enables Catalytic Formation of Weak Chemical Bonds with Molecular Hydrogen.

Park, Y.; Kim, S.; Tian, L.; Zhong, H.; Scholes, G. D.; Chirik, P. J.

Nature Chem. 2021, 13, 969-976.

Highlighted by Princeton University.

[24] Synthesis, Electronic Structure, and Reactivity of a Planar Four-Coordinate, Cobalt-Imido Complex.

Park, Y.; Semproni, S. P.; Zhong, H. Chirik, P. J.

Angew. Chem. Int. Ed. 2021, 60, 14376-14380.

[23] Visible-Light-Enhanced Cobalt-Catalyzed Hydrogenations: Switchable Catalysis Enabled by Divergence between Thermal and Photochemical Pathways

Mendelsohn, L. N.; MacNeil, C. S.; Tian, L.; Park, Y.; Scholes, G. D.; Chirik, P. J.

ACS Catal. 2021, 11, 1351.

[22] The Future of Scientific Leadership is Interdisciplinary: The 2019 CAS Future Leaders Share Their Vision. (Backstory Article)

Milić, J.V.; Ehnbom, A.; Garedew, M.; Vincent-Ruz, P.; Schloemer, T.H.; Hodgson, G. K.; Oakley, M.S.; Sasaki, K.; Chander, S.; Lé garé, M.-A.; Callmann, C. E.; Bismillah, A. N.; van Osch, D.J.G.P.; Sanchez, V.; Boase, N.R.B.; Mambwe, D.; Coley, C.W.; Deng, Y.; Betz, K.N.; Sanjosé-Orduna, J.; Natoli, S.; Zhang, L.; Bakulina, O.; Fereyduni, E.; Hilario-Martínez, J.C.; Busta, L.; Hunter, A.; Park, Y.; Zadeh, F. H. iScience 2020, 23, 101442.

[21] Catalytic Hydrogenation of a Manganese(V) Nitride to Ammonia.

Kim, S.; Zhong, H.; Park, Y.; Loose, F.; Chirik, P. J.

J. Am. Chem. Soc. 2020, 142, 9518–9524.

Graduate and Undergraduate Works

The Park Laboratory

Graduate and Undergraduate Works

[20] Harnessing Secondary Coordination Sphere Interactions that Enable the Selective Amidation of Benzylic C−H Bonds.

Jung, H.; Schrader, M.; Kim, D.; Baik, M.-H.*; Park, Y.*; Chang, S.*

J. Am. Chem. Soc. 2019, 141, 15356–15366. (*Co-corresponding authors).

[19] Asymmetric Formation of of γ-Lactams via C–H Amidation Enabled by Chiral Hydrogen-Bond-Donor Catalysts

Park, Y. & Chang, S.

Nature Catal. 2019, 2, 219.

Highlighted in News & Views of Nature Catalysis.

2020년 대한민국 국가연구개발 우수성과 100선 선정.

[18] Iridium-Catalyzed Enantioselective C(sp³)–H Amidation Controlled by Attractive Noncovalent Interactions.

Wang, H.; Park, Y.; Bai, Z.; Chang, S.; He, G.; Chen, G.

J. Am. Chem. Soc. 2019,141, 7194–7201.

[17] Ni-Mediated Generation of "CN" Unit from Formamide and Its Catalysis in the Cyanation Reactions.

Yang, L.; Liu, Y.-T.; Park, Y.; Park, S.-W., Chang, S.

ACS Catal. 2019, 9, 3360–3365.

[16] Revisiting Arene C(sp²)–H Amidation via Intramolecular Transfer of Iridium Nitrenoids: Evidence for a Spirocyclization Pathway.

Hwang, Y.†; Park, Y.†; Kim, Y.B.; Kim, D.; Chang, S.

Angew. Chem. Int. Ed. 2018, 57, 13565–13569 (†Co-first authors).

[15] Selective Formation of γ-Lactams via C–H Amidation Enabled by Tailored Iridium Catalysts.

Hong, S. Y.†; Park, Y.†; Hwang, Y.; Kim, Y.; Baik, M.-H.; Chang, S.

Science 2018, 359, 1016–1021 (†Co-first authors).

Highlighted in Nature, Synfacts, Organic Chemistry Portal, and Science Daily.

[14] Delineating Physical Organic Parameters in Site-Selective C–H Functionalization of Indoles.

Kim, Y.†; Park, Y.†; Chang, S.

ACS Cent. Sci. 2018, 4, 768–775 (†Co-first authors).

[13] Quantifying Structural Effects of Amino Acid Ligands in Pd(II)-Catalyzed Enantioselective C–H Functionalization Reactions

Park, Y.; Niemeyer, Z. L.; Yu, J.-Q.; Sigman, M. S.

Organometallics 2018, 37, 203–210.
Featured as a Cover Art in Volume 37, Issue 2.

[12] Iridium-Catalysed Arylation of C–H Bonds Enabled by Oxidatively Induced Reductive Elimination.

Shin, K.; Park, Y.; Baik, M.-H.; Chang, S.

Nat. Chem. 2018, 10, 218–224.

[11] Transition Metal-Catalyzed C–H Amination: Scope, Mechanism & Applications. (Review Article)

Park, Y.; Kim, Y.; Chang, S.

Chem. Rev. 2017, 117, 9247–9301.

Special issue for C-H activation.

[10] Mechanism-Driven Approach to Develop a Mild and Versatile C–H Amidation through Ir(III) Catalysis.

Hwang, Y.†; Park, Y.†; Chang, S.

Chem. Eur. J. 2017, 23, 11147–11152 (†Co-first author).

[9] Why is the Ir(III)-Mediated Amido Transfer So Much Faster than the Rh(III)-Mediated Reaction? A Combined Experimental and Computational Study.

Park, Y.; Heo, J.; Baik, M.-H.; Chang, S.

J. Am. Chem. Soc. 2016, 138, 14020–14029.

[8] The Mechanism of Rh-Catalyzed Oxidative Cyclizations: Closed vs. Open Shell Pathways.

Park, Y.; Ahn, S.; Kang, D.; Baik, M.-H.

Acc. Chem. Res. 2016, 49, 1263–1270.

[7] Study of Sustainability and Scalability in the Cp*Rh(III)-Catalyzed Direct C–H Amidation with 1,4,2-Dioxazol-5-ones.

Park, Y.; Jee, S.; Kim, J. G.; Chang, S.

Org. Process Res. Dev. 2015, 19, 1024–1029.

Selected as ACS Editors’ Choice.

[6] Mechanistic Studies on the Rh(III)-Mediated Amido Transfer Process Leading to Robust C–H Amination with a New Type of Amidating Reagent.

Park, Y.; Park, K. T.; Kim, J. G.; Chang, S.

J. Am. Chem. Soc. 2015, 137, 4534–4542.

[5] Rh(III)-Catalyzed Traceless Coupling of Quinoline N-Oxides with Internal Diarylalkynes.

Sharma, U.; Park, Y.; Chang, S.

J. Org. Chem. 2014, 79, 9899–9906.

[4] Mechanistic Studies of the Rhodium-Catalyzed Direct C–H Amination Reaction Using Azides as the Nitrogen Source

Park, S. H.; Kwak, J.; Shin, K. Ryu, J.; Park, Y.; Chang, S.

J. Am. Chem. Soc. 2014, 136, 2492–2502.

[3] Regiodivergent Access to Five- and Six-Membered Benzo-Fused Lactams: Ru-Catalyzed Olefin Hydrocarbamoylation.

Li, B.; Park, Y.; Chang, S.

J. Am. Chem. Soc. 2014, 136, 1125–1131.

[2] Rhodium-Catalyzed Direct Amination of Arene C–H Bonds Using Azides as the Nitrogen Source.

Park, S. H.; Park, Y.; Chang, S.

Org. Synth. 2014, 91, 52–59.

[1] Discovery of New Benzothiazole-Based Inhibitors of Breakpoint Cluster Region-Abelson Kinase Including the T315I Mutant.

Hong S.; Kim J.; Yun, S.-M.; Lee, H.; Park, Y.; Hong, S.-S.; Hong, S.

J. Med. Chem. 2013, 56, 3531–3545.

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© The Park Laboratory, 2023.

Address: Rm. 604, E6-6, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea

© The Park Laboratory, 2023.

Address: Rm. 604, E6-6, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea